Last reviewed: August 2026
No. Dogs should never eat grapes, raisins, currants, or sultanas. There is no known safe amount — even a few grapes have caused acute kidney failure in some dogs. If your dog has eaten any amount, contact a vet immediately, even if they seem fine.
For over 20 years vets knew grapes and raisins could cause kidney failure in dogs but didn't know why. Research published between 2022 and 2025 has narrowed this to tartaric acid, a compound found in grape flesh at 0.35–2% concentration depending on variety, ripeness, and growing conditions.
The key detail: dogs lack a kidney transporter protein called OAT4 that humans use to clear tartaric acid. Without it, the acid lingers in kidney cells, where lab studies show it disrupts mitochondrial energy production until the cells die — a process called proximal tubular necrosis. This is also why cats, which retain some OAT4 activity, react far less severely than dogs do to the same exposure.
Unusually for a food toxicity, this one doesn't follow predictable breed or size patterns — it's described as idiosyncratic. A Chihuahua and a Great Dane face comparable relative risk. Don't assume a larger dog is safer.
| Time after ingestion | What to expect |
|---|---|
| 6–12 hours | Vomiting, diarrhoea, lethargy, loss of appetite |
| 12–24 hours | Abdominal pain, dehydration, weakness, tremors |
| 24–48 hours | Kidney injury signs begin: reduced or absent urination, continued vomiting |
Some dogs show no symptoms in the first 24 hours yet still develop kidney injury — this is why treatment is based on exposure, not on whether symptoms have appeared.
South Africa: Contact your nearest 24-hour emergency vet clinic immediately, or your regular vet's after-hours line.
ASPCA Animal Poison Control (US, reference only): +1-888-426-4435 — typically charges a consultation fee for non-US callers.
This page is general educational information, not a substitute for veterinary advice. If your dog has ingested grapes or raisins, contact a veterinarian immediately.